abstract：BACKGROUND:Type 2 Diabetes Mellitus (T2DM) patients are increasingly using herbal remedies due to the fact that sticking to the therapeutic regimens is becoming awkward. However, studies towards herbal medicine use by diabetic patients is scarce in Ethiopia. Therefore, the aim of the current study was to explore the pr...

journal_title：BMC complementary and alternative medicine

authors： Mekuria AB,Belachew SA,Tegegn HG,Ali DS,Netere AK,Lemlemu E,Erku DA

更新日期：2018-03-09 00:00:00

abstract：BACKGROUND:Salix aegyptiaca is known for its medicinal properties mainly due to the presence of salicylate compounds. However, it also contains other beneficial phytochemicals such as gallic acid, quercetin, rutin and vanillin. The aim of the study was to examine the redox potential, antioxidant and anti-inflammatory a...

journal_title：BMC complementary and alternative medicine

authors： Nauman M,Kale RK,Singh RP

更新日期：2018-03-07 00:00:00

abstract：BACKGROUND:Saliva is fundamental to our oral health and our well-being. Many factors can impair saliva secretion, such as adverse effects of prescribed medication, auto-immune diseases (for example Sjögren's syndrome) and radiotherapy for head and neck cancers. Several studies have suggested a positive effect of acupun...

journal_title：BMC complementary and alternative medicine

authors： Assy Z,Brand HS

更新日期：2018-02-13 00:00:00

abstract：BACKGROUND:Breast cancer remains a leading cause of death in women worldwide. Although breast cancer therapies have greatly advanced in recent years, many patients still develop tumour recurrence and metastasis, and eventually succumb to the disease due to chemoresistance. Citral has been reported to show cytotoxic eff...

journal_title：BMC complementary and alternative medicine

authors： Nigjeh SE,Yeap SK,Nordin N,Kamalideghan B,Ky H,Rosli R

更新日期：2018-02-13 00:00:00

abstract：BACKGROUND:Betulinic acid (BA) is a natural triterpenoid compound and exhibits a wide range of biological and medicinal properties including anti-inflammatory activity. Therefore, this theoretical investigation is performed to evaluate (a) physicochemical properties such as acid dissociation constant (pKa), distributio...

journal_title：BMC complementary and alternative medicine

authors： Khan MF,Nahar N,Rashid RB,Chowdhury A,Rashid MA

更新日期：2018-02-02 00:00:00

abstract：BACKGROUND:Storage lower urinary tract symptoms (LUTS) including overactive bladder (OAB) and urinary incontinence (UI) affect millions of people worldwide, significantly impacting quality of life. Plant based medicines have been documented both empirically and in emerging scientific research to have varying benefits i...

journal_title：BMC complementary and alternative medicine

authors： Schoendorfer N,Sharp N,Seipel T,Schauss AG,Ahuja KDK

更新日期：2018-01-31 00:00:00

abstract：BACKGROUND:On account of deterioration of chronic heart failure (CHF) and extensive exploration of Chinese herbal injections (CHIs), we performed a network meta-analysis to investigate the efficacy of CHIs (Huangqi injection, Shenfu injection, Shengmai injection, Shenmai injection, Shenqi Fuzheng injection, Yiqifumai i...

journal_title：BMC complementary and alternative medicine

authors： Wang KH,Wu JR,Zhang D,Duan XJ,Ni MW

更新日期：2018-01-31 00:00:00

abstract：BACKGROUND:Sheng-ji Hua-yu(SJHY) formula is one of the most useful Traditional Chinese medicine (TCM) in the treatment of the delayed diabetic wound. However, elucidating the related molecular biological mechanism of how the SJHY Formula affects excessive inflammation in the process of re-epithelialization of diabetic ...

journal_title：BMC complementary and alternative medicine

authors： Kuai L,Zhang JT,Deng Y,Xu S,Xu XZ,Wu MF,Guo DJ,Chen Y,Wu RJ,Zhao XQ,Nian H,Li B,Li FL

更新日期：2018-01-29 00:00:00

abstract：CORRECTION:After the publication of this article [1] it came to our attention that Harquin Simplice Foyet was incorrectly included as Harquin Simplice Harquin Foyet. The corrected name is included in the author list. The original article was updated. ...

journal_title：BMC complementary and alternative medicine

authors： Foyet HS,Deffo ST,Yewo PK,Antioch I,Zingue S,Asongalem EA,Kamtchouing P,Ciobica A

更新日期：2017-12-28 00:00:00

abstract：BACKGROUND:"Horchata" is an herbal mixture infusion consumed in Southern Ecuador; 66% of its plants are anti-inflammatory medicinal plant, and 51% are analgesics. Anti-inflammatory substances can prevent carcinogenesis mediated by cytotoxic effects and can prevent DNA damage. The aim of this study was to evaluate the c...

journal_title：BMC complementary and alternative medicine

authors： Bailon-Moscoso N,Tinitana F,Martínez-Espinosa R,Jaramillo-Velez A,Palacio-Arpi A,Aguilar-Hernandez J,Romero-Benavides JC

更新日期：2017-12-19 00:00:00

abstract：BACKGROUND:Blood stasis syndrome (BSS) is a general pattern identification and refers to pathological stagnation of blood circulation, dysfunction of endothelial cells or metabolic disorder in traditional Korean medicine (TKM). Dohongsamul-Tang (DHSMT) is a well-known traditional herbal formula which used for treatment...

journal_title：BMC complementary and alternative medicine

authors： Shim EH,Lee H,Lee MS,You S

更新日期：2017-12-19 00:00:00

abstract：BACKGROUND:Various plant extracts have been suggested to be used as auxiliary agents in chemotherapy considering their anti-proliferative effect on cancer cells. However, recent reports reveal that plant extracts may function as inducers of autophagy of cancer cells. In general, autophagy confers survival advantage for...

journal_title：BMC complementary and alternative medicine

authors： Li H,Chen C

更新日期：2017-12-16 00:00:00

abstract：BACKGROUND:Quercetin (QCT) is a flavonol present in many vegetables, it is proved to show chemo preventive effect against lung, cervical, prostate, breast and colon cancer due to its anti-inflammatory, anti-tumor and anti-oxidant property. Looking into the reported chemo-preventive effect we speculated antitumor activi...

journal_title：BMC complementary and alternative medicine

authors： Liu H,Zhou M

更新日期：2017-12-13 00:00:00

abstract：BACKGROUND:Conventional therapy (CT) such as donepezil and memantine are well-known short-term treatments for the symptoms of Alzheimer's disease (AD). The efficacy of them, however, drops below baseline level after 9 months. In China, herbal therapy as a complementary therapy is very popular. Should conventional thera...

journal_title：BMC complementary and alternative medicine

authors： Shi J,Ni J,Lu T,Zhang X,Wei M,Li T,Liu W,Wang Y,Shi Y,Tian J

更新日期：2017-12-13 00:00:00

abstract：BACKGROUND:Galetin 3,6-dimethyl ether (FGAL) is a flavonoid isolated from aerial parts of Piptadenia stipulacea. Previously, FGAL was shown to inhibit both carbachol- and oxytocin-induced phasic contractions in the rat uterus, which was more potent with oxytocin. Thus, in this study, we aimed to investigate the tocolyt...

journal_title：BMC complementary and alternative medicine

authors： Carreiro JDN,Souza ILL,Pereira JC,Vasconcelos LHC,Travassos RA,Santos BVO,Silva BAD

更新日期：2017-12-02 00:00:00

abstract：BACKGROUND:Conventional scientific studies had supported the use of polysaccharides and β-glucans from a number of fungi, including Ganoderma lucidum for the treatment of recurrent oral ulceration (ROU). Our aim of the present study was to evaluate whether freeze-dried powder from G. lucidum mycelia (FDPGLM) prevents R...

journal_title：BMC complementary and alternative medicine

authors： Xie L,Zhong X,Liu D,Liu L,Xia Z

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Paclitaxel (taxol) is a potent anticancer drug that is used in the treatment of a wide variety of cancerous. In the present study, we identified a taxol derivative named 7-epi-10-deacetyltaxol (EDT) from the culture of an endophytic fungus Pestalotiopsis microspora isolated from the bark of Taxodium mucronat...

journal_title：BMC complementary and alternative medicine

authors： Subban K,Singh S,Subramani R,Johnpaul M,Chelliah J

更新日期：2017-11-28 00:00:00

abstract：BACKGROUND:We previously reported that a methanol extract of Glycyrrhizae radix (MEGR) blocked methamphetamine-induced locomotor sensitization and conditioned place preference in rats. In the present study, the effects of MEGR on repeated nicotine-induced locomotor sensitization and enhanced extracellular dopamine (DA)...

journal_title：BMC complementary and alternative medicine

authors： Zhao ZL,Kim SC,Liu HF,Wu YY,Li LB,Wang YH,Jiao Y,Fan Y,Lee CW,Lee BH,Cho IJ,Yang CH,Zhao RJ

更新日期：2017-11-16 00:00:00

abstract：BACKGROUND:Melastoma malabathricum L. (family Melastomaceae; MM) and Muntingia calabura L. (family Elaeocarpaceae; MC) have been separately reported to possess gastroprotective activity. In an attempt to develop a pharmaceutical product with antiulcer potential, the synergistic gastroprotective activity of methanolic e...

journal_title：BMC complementary and alternative medicine

authors： Halim SZ,Zakaria ZA,Omar MH,Mohtarrudin N,Wahab IRA,Abdullah MNH

更新日期：2017-11-09 00:00:00

abstract：BACKGROUND:Ultraviolet radiation from sunlight induces overproduction of reactive oxygen species (ROS) resulting in skin photoaging and hyperpigmentation disorders. Novel whitening and anti-wrinkle compounds from natural products have recently become of increasing interest. The purpose of this study was to find product...

journal_title：BMC complementary and alternative medicine

authors： Chatatikun M,Chiabchalard A

更新日期：2017-11-09 00:00:00

abstract：BACKGROUND:Chinese herbal medicine formula Yu ping feng san (YPFS) is commonly used for allergic rhinitis (AR). Previous review had summarized the effectiveness and safety of YPFS, however without any subgroup analysis performed to provide detailed evidence for guiding clinical practice. YPFS was recommended for the ma...

journal_title：BMC complementary and alternative medicine

authors： Luo Q,Zhang CS,Yang L,Zhang AL,Guo X,Xue CC,Lu C

更新日期：2017-11-06 00:00:00

abstract：BACKGROUND:Although various treatments for breast cancer related lymphedema exist, there is still a need for a more effective and convenient approach. Pilot studies and our clinical observations suggested that acupuncture may be a potential option. This study aims to verify the effectiveness of acupuncture on BCRL and ...

journal_title：BMC complementary and alternative medicine

authors： Zhu H,Li J,Peng Z,Huang Y,Lv X,Song L,Zhou G,Lin S,Chen J,He B,Qin F,Liu X,Dai M,Zou Y,Dai S

更新日期：2017-09-21 00:00:00

abstract：BACKGROUND:Tinospora cordifolia (Guduchi or Amrita) is an important drug of Ayurvedic System of Medicine and found mention in various classical texts for the treatment of diseases such as jaundice, fever, diabetes, cancer and skin disease etc. In view of its traditional claims, antioxidant and anti-proliferative activi...

journal_title：BMC complementary and alternative medicine

authors： Polu PR,Nayanbhirama U,Khan S,Maheswari R

更新日期：2017-09-11 00:00:00

abstract：BACKGROUND:Previous studies have revealed that gypenosides (GPS) improve the symptoms of anxiety disorders in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned rat model of Parkinson's disease (PD). The present study aimed to investigate the effects of GPS on memory deficits in an MPTP-lesioned mouse model...

journal_title：BMC complementary and alternative medicine

authors： Zhao TT,Kim KS,Shin KS,Park HJ,Kim HJ,Lee KE,Lee MK

更新日期：2017-09-06 00:00:00

abstract：BACKGROUND:Although it has been reported to contain high polyphenols, the pharmacological studies of the calyx of Diospyros kaki Thunb (DKC) have not been elucidated in detail. In this study, we elucidated anti-cancer activity and potential molecular mechanism of DKC against human colorectal cancer cells. METHODS:Anti...

journal_title：BMC complementary and alternative medicine

authors： Park SB,Park GH,Song HM,Son HJ,Um Y,Kim HS,Jeong JB

更新日期：2017-09-05 00:00:00

abstract：BACKGROUND:Approximately 11% of the German population are convinced that certain moon phases and moon signs may impact their health and the onset and clinical course of diseases. Before elective surgery, a considerable number of patients look to optimize the timing of the procedure based on the lunar cycle. Especially ...

journal_title：BMC complementary and alternative medicine

authors： Kleespies A,Mikhailov M,Khalil PN,Pratschke S,Khandoga A,Stangl M,Illner WD,Angele MK,Jauch KW,Guba M,Werner J,Rentsch M

更新日期：2017-09-04 00:00:00

abstract：BACKGROUND:To examine whether the use of Sasang constitutional (SC) types, such as Tae-yang (TY), Tae-eum (TE), So-yang (SY), and So-eum (SE) types, increases the accuracy of risk prediction for metabolic syndrome. METHODS:From 2001 to 2014, 3529 individuals aged 40 to 69 years participated in a longitudinal prospecti...

journal_title：BMC complementary and alternative medicine

authors： Lee S,Lee SK,Kim JY,Cho N,Shin C

更新日期：2017-09-02 00:00:00

abstract：BACKGROUND:P-113 (AKRHHGYKRKFH-NH2) is a 12-amino-acid histidine-rich peptide derived from histatin 5 that is highly degradable in high salt concentrations and biological fluids such as serum, plasma and saliva. Nal-P-113, a novel antimicrobial peptide whose histidine residues are replaced by the bulky amino acids β-na...

journal_title：BMC complementary and alternative medicine

authors： Wang HY,Lin L,Fu W,Yu HY,Yu N,Tan LS,Cheng JW,Pan YP

更新日期：2017-08-29 00:00:00

abstract：BACKGROUND:Euphorbia hirta linn., is a species of Euphorbiaceae family. They are known as asthma plant, barokhervi. The plant E. hirta is famous for its medicinal importance among the tribal population. It is a common practice to use the whole to heal wounds. Several pharmacological properties including antiseptic, ant...

journal_title：BMC complementary and alternative medicine

authors： Tuhin RH,Begum MM,Rahman MS,Karim R,Begum T,Ahmed SU,Mostofa R,Hossain A,Abdel-Daim M,Begum R

更新日期：2017-08-24 00:00:00

abstract：BACKGROUND:Electroacupuncture (EA) has been applied to treat and prevent diseases for years. However, molecular events happened in both the acupunctured site and the internal organs after EA stimulation have not been clarified. METHODS:Here we applied transcriptomic analysis to explore the gene expression signatures a...

journal_title：BMC complementary and alternative medicine

authors： Wu JS,Lo HY,Li CC,Chen FY,Hsiang CY,Ho TY

更新日期：2017-08-15 00:00:00

abstract：BACKGROUND:Type 2 diabetes mellitus (T2DM) is a major risk factor for cardiovascular disease, and the prevalence has increased significantly in recent decades to epidemic proportions in China. Individually, fenugreek (Trigonella foenum graecum) seed, mulberry (Morus alba L.) leaf and American ginseng (Panax quinquefoli...

journal_title：BMC complementary and alternative medicine

authors： Kan J,Velliquette RA,Grann K,Burns CR,Scholten J,Tian F,Zhang Q,Gui M

更新日期：2017-07-05 00:00:00

abstract：BACKGROUND:Cancer-related fatigue is one of the most common symptoms experienced by cancer patients, and it diminishes their quality of life. However, there is currently no confirmed standard treatment for cancer-related fatigue, and thus, many patients who suffer cancer-related fatigue seek complementary and alternati...

journal_title：BMC complementary and alternative medicine

authors： Kim M,Kim JE,Lee HY,Kim AR,Park HJ,Kwon OJ,Kim EJ,Park YC,Seo BK,Cho JH,Kim JH

更新日期：2017-07-05 00:00:00

abstract：BACKGROUND:The psychophysical responses induced by verum acupuncture are characterized by a constellation of unique subjective sensory responses commonly termed De Qi. Furthermore, a variety of sham interventions have been used as a control for acupuncture clinical trials. Indeed, one such control has been mock laser w...

journal_title：BMC complementary and alternative medicine

authors： Razavy S,Gadau M,Zhang SP,Wang FC,Bangrazi S,Berle C,Harahap M,Li T,Li WH,Zaslawski C

更新日期：2017-07-03 00:00:00

abstract：BACKGROUND:Infectious diseases are the most common causes of morbidity and mortality in developing countries. Wound and wound infections are also major health problem. Nowadays, medicinal plants play a major role in treatment of infectious diseases and wound healing and they are easily available and more affordable as ...

journal_title：BMC complementary and alternative medicine

authors： Begashaw B,Mishra B,Tsegaw A,Shewamene Z

更新日期：2017-06-26 00:00:00

abstract：BACKGROUND:Ginger is a popular spice and food preservative. The rhizomes of the common ginger have been used as traditional medicine to treat various ailments. 6-Shogaol, a pungent compound isolated from the rhizomes of jahe gajah (Zingiber officinale var officinale) has shown numerous pharmacological activities, inclu...

journal_title：BMC complementary and alternative medicine

authors： Seow SLS,Hong SL,Lee GS,Malek SNA,Sabaratnam V

更新日期：2017-06-24 00:00:00

abstract：BACKGROUND:Honey, alone or in combination, has been used for wound healing since ancient times and has reemerged as a topic of interest in the last decade. Pectin has recently been investigated for its use in various biomedical applications such as drug delivery, skin protection, and scaffolding for cells. The aim of t...

journal_title：BMC complementary and alternative medicine

authors： Giusto G,Vercelli C,Comino F,Caramello V,Tursi M,Gandini M

更新日期：2017-05-16 00:00:00

abstract：BACKGROUND:The use of dietary supplements (DS) is common among persons with dementia. Direct risks associated with DS use include adverse events and DS-drug interactions. A direct risk is a risk caused by the treatment itself. Indirect risks are related to the treatment setting, such as the conditions of use, and not t...

journal_title：BMC complementary and alternative medicine

authors： Risvoll H,Giverhaug T,Halvorsen KH,Waaseth M,Musial F

更新日期：2017-05-12 00:00:00

abstract：BACKGROUND:Medicinal plants are rich source of traditional herbal medicine around the globe. Most of the plant's therapeutic properties are due to the presence of secondary bioactive compounds. METHODS:The present study analyzed the High Pressure Liquid Chromatography (HPLC) fractions of Puncia granatum (peel) extract...

journal_title：BMC complementary and alternative medicine

authors： Khan I,Rahman H,Abd El-Salam NM,Tawab A,Hussain A,Khan TA,Khan UA,Qasim M,Adnan M,Azizullah A,Murad W,Jalal A,Muhammad N,Ullah R

更新日期：2017-05-03 00:00:00

abstract：BACKGROUND:Despite substantial advances in pain research and treatment, millions of people continue to suffer from pain and this has been attributed mainly to the unavailability of effective and safer analgesics. The use of plants as medicines is still widespread and plants constitute a large source of novel phytocompo...

journal_title：BMC complementary and alternative medicine

authors： Boakye-Gyasi E,Henneh IT,Abotsi WKM,Ameyaw EO,Woode E

更新日期：2017-04-26 00:00:00

abstract：BACKGROUND:Although the anti-diabetic activity of Aegle marmelos (AM) is known, however, its anti-glycation activity is not reported yet. In this study, we have investigated its anti-glycation activity under in vitro and in vivo conditions and determined possible mechanism(s) in streptozotocin-induced diabetic rats. M...

journal_title：BMC complementary and alternative medicine

authors： Hafizur RM,Momin S,Fatima N

更新日期：2017-04-21 00:00:00